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10.1038/s42255-024-01068-x 79 RakipovskiG.RolinB.NohrJ.KleweI.FrederiksenK

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A clinically significant interaction exists between tirzepatide and oral contraceptives, requiring backup contraception for 4 weeks after initiation and each dose increase, and patients taking levothyroxine or other time-sensitive medications warrant closer monitoring

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