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In a model of non-ischemic HF in dogs (tachycardiomyopathy induced by pacemakers), IV infusion of GLP-1 increases left ventricular (LV) contractility (LV dP/dt increased by 98%, stroke volume by 102%, and cardiac output by 57%) and decreases LV end-diastolic pressure, heart rate, and systemic vascular resistance
The main parameter measured was latency, which refers to the time the animal takes to initiate and complete a specific action during the test (Fig
Within this framework, absorption can be considered a metabolic control module: even when dietary composition appears adequate, altered gastrointestinal kinetics may reduce effective delivery of critical substrates, shifting metabolic constraint from nutrient intake to handling efficiency
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The effect of Helicobacter pylori eradication on the natural course of atrophic gastritis with dysplasia
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