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Understanding how long it takes for GLP-1 to kick in helps set realistic expectations for treatment outcomes
Due to their large molecular weight and hydrophilic nature, GLP1 agonists face challenges with oral delivery, including poor and variable gastrointestinal absorption, leading to low bioavailability
The study found that for every one-unit increase in BMI, total testosterone decreased by approximately 2% (Grossmann, 2014, Clinical Endocrinology )
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