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The parallel is not hypothetical
The co-primary endpoints were the percentage change of weight reduction in the Tirzepatide 10mg and 15mg dose groups at week 72 and the percentage of participants achieving 5% body weight reduction at 72 weeks compared to placebo
In the SURMOUNT-1 trial, tirzepatide at the highest dose (15 mg) produced average weight loss of 22.5% versus approximately 15% for semaglutide in comparable trials
Experiment with timing and consult your provider to see what works best for you
A washout period is the off-cycle interval during which ipamorelin is withheld entirely, allowing GHS-R1a receptor density to recover
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