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The p53 protein itself acts as an intrinsic regulator within the cell, primarily tasked with overseeing the cell cycle's progression, including the initiation of cell death
Furthermore, it is involved in vital cellular functions like immune system modulation, DNA synthesis and repair, and appropriate enzyme functionall of which are necessary for preserving general health
Compared to WT HMOX2, the ubiquitination of the HMOX2 K68R mutant was not enhanced by MITOL (Fig
She has provided consultation to INmune Bio, Merck, Calico, Forward Therapeutics, Jaya, SciNeuro, NysnoBio, Longevity Biotech, Sanofi, iMetabolic Pharma, Novo Nordisk and iMMvention
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