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Retatrutide is investigational and not FDA-approved for any use as of 2026
Mounjaro itself doesnt directly alter reproductive hormones, but the weight loss it causes can affect hormone levels
Sanchez C et al
Its proven ability to improve blood sugar control makes it a standard part of treatment plans for many patients
While medications maintain sustained, supraphysiologic hormone levels and typically produce significant weight reduction and HbA1c decreases, food-stimulated GLP-1 is released in brief pulses after meals and rapidly degraded within minutes, resulting in smaller metabolic improvements
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