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1 The investigators do believe that because NAION is a potentially debilitating ophthalmic condition, gaining a clearer understanding of its incidence and the factors influencing its occurrence would enhance care for those considering the use of these medications, they wrote

Its intended for adults who meet specific Body Mass Index (BMI) criteria: either a BMI of 30 or higher (considered obese), or a BMI of 27 or higher (considered overweight) in conjunction with at least one weight-related health condition

That was my biggest downfall. Nature 638 , 308-310 (2025) doi: References Jastreboff, A

This dual action distinguishes tirzepatide from single GLP-1 receptor agonists and contributes to its efficacy in glycaemic control and weight reduction