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In ovarian pathology, ROS overload in follicular fluid first activates the ER stress sensor PERK, promoting phosphorylation of the eukaryotic translation initiation factor eIF2
The most common side effects are gastrointestinal nausea, loose stools, or constipation and occur primarily during dose increases
10.1053/j.gastro.2011.10.028 131 MohammedF
Focus on Hydration and Protein Intake Patients involved in wellness or weight loss programs sometimes unintentionally under-eat or become dehydrated
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