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FM organized the database, performed the statistical analysis, and wrote the first draft of the manuscript

Furthermore, its direct detoxification effects solidify this effect on cellular health as it helps protect cells from various stressors

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Following the concrete conceptualization of the BBB, which was developed by Paul Ehrlich, Edwin Goldmann, and Lena Stern, extensive and ongoing studies have been conducted on its morphology, molecular composition, and physiological properties [5]

The Nrf2-Keap1 pathway is another key regulator, turning on genes that drive glutathione production and detoxification