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The peptide contains no cysteine but does have susceptible backbone amide bonds and side-chain groups that can be oxidized under ambient conditions

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This upregulation of the GH receptor potentiated the proliferative effects of growth hormone, as evidenced by increased cell proliferation (MTT assay) and proliferating cell nuclear antigen (PCNA) expression

Oral retinoids should not be used by women who are pregnant or may become pregnant since they may cause birth defects (Schalock 2014