Angiogenesis Applied to investigate blood-vessel formation pathways associated with both components
This observation reflects a long-term cancer risk association rather than a treatment-emergent adverse effect profile, and detailed adverse event data were not reported in the cited study
2013c;38(8):125970
In mouse models, scientists found that drugs such as tirzepatide, which act on both glucose-dependent insulinotropic polypeptide (GIP) and GLP-1 receptors, could reduce tumor growth
With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success." The study, "Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty," obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023