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Secondary effects have been documented on mast cells, endothelial cells (blood vessel formation), and the small population of dermal stem cells associated with the hair follicle bulge 1
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Two common culprits that often cause discomfort are skin allergies and fungal infections
Disruption or delocalization of ZO-1, occludin, and claudin-5 has been observed in vitro in endothelial cells infected with N
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