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Role of glucagon-like peptides in inflammatory bowel diseasescurrent knowledge and future perspectives

However, the same molecules can also bind to nociceptive receptors in the brain, and this interaction may be responsible for nausea experienced by a high proportion of patients, which can result in high numbers of patients discontinuing treatment after initiation

When the host produces antibodies against these viral antigens, the antibodies also bind to ACTH, limiting the host stress response by decreasing the ability to stimulate corticosteroid secretion (42)