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By hitting both receptors, tirzepatide produces a more pronounced effect on satiety and glucose control than single-agonist compounds like semaglutide
GLP1 receptor agonists such as liraglutide, semaglutide, and dulaglutide are widely used in the management of type 2 diabetes and increasingly for weight management in people with and without diabetes
doi:10.1016/S0140-6736(20)32549-6 5
Some researchers believe that the dominance of this pathway alone may be even more important than the sheer numbers of estrogen metabolites produced in the body
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