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They developed a new kind of DAC by conjugating a PROTAC that degrades BRD4 with an ROR1 antibody (Fig
Compared to normal epithelial breast cells, these effects are specific to cancer cells [112]
Some are already widely used as medicines
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Topical treatments such as capsaicin or lidocaine that can be spread on the skin or used as a patch can help relieve localized pain but can cause skin irritation, burning, and redness at the application site
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