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Eye Issues High homocysteine (Hcy) levels are linked to eye problems like retinopathy, optic nerve damage, and glaucoma
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Even further, a 2020 meta-analysis found a significant reduction of body weight associated with berberine intake
BCKAs can be metabolized by BCKDH to branched-chain acyl-CoA, and blocking this step causes serious metabolic disorders, such as maple syrup urine disease (Xu et al., 2020) and propionic academia (Chen et al., 2017)
The compounded gastrointestinal effects represent a significant concern
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