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Aging is one reason
Over time, this protection gives you clearer skin and an even tone
To model Leydig cell senescence in vitro, TM3 mouse Leydig cells were treated with hydrogen peroxide (H2O2)
Versus retinol and retinoic acid (cosmetic anti-ageing reference): retinol acts via RAR/RXR receptors and transcriptional modulation but with irritating effects (desquamation, solar sensitivity)
Additionally, combining it with low-level peptides like pal-tetrapeptide-7 enhances matrix signaling without irritation
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