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Dose escalation occurs every 4 weeks if tolerated, following a gradual titration schedule to minimize gastrointestinal side effects
This is why its effects are so broad and why it has accumulated a larger research base than almost any other cosmetic peptide
(Scientific American, 2023)
Micronutrient adequacy requires attention, particularly for vitamins B12, D, iron, calcium, and folate
Both are titrated as well, meaning you start with a low dosage to test tolerance and gradually ramp up over a period of weeks to the dose that's right for you
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