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The trial was well designed, including levodopa-naive patients to avoid any confounding effect of dopaminergic therapies (something that the previous trials had not done)

The effects of galantamine and buspirone on sleep structure: Implications for understanding sleep abnormalities in major depression

The American Diabetes Association Standards of Care emphasize the importance of monitoring for adverse effects and adjusting treatment as needed to optimize tolerability while maintaining therapeutic benefit

Magnesium glycinate is often recommended for better sleep, as the amino acid glycine also has a calming effect on the brain