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Carnitine deficiency has been associated with heart failure [5]

Abbreviations GLP-1 RAs: Glucagon-like peptide-1 receptor agonists T2DM: Type 2 diabetes mellitus COPD: Chronic obstructive pulmonary disease BMI: Body mass index HbA1c: Glycated hemoglobin RR: Relative risk CI: Confidence interval RCT: Randomized controlled trial CVOT: Cardiovascular outcome trial PRISMA: Preferred reporting items for systematic reviews and meta-analyses References Zar HJ, Ferkol TW

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The improved solubility and stability facilitate the successful determination of the three-dimensional structure of proteins, which is essential for understanding their function and for drug design

In a case-control study involving 105 patients [43] , heterozygous MC4R pathogenic/likely pathogenic (P/LP) variant carriers exhibited similar maximum total body weight loss percentage (%TBWLmax) to non-carriers (28.3% 8.5% vs