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As the disease progresses, additional brain regions involved in higher cognitive functions are affected, leading to more widespread cognitive and behavioral impairments ( 4 Biochemical and molecular mechanisms in PD Parkinsons disease is a chronic neurodegenerative disorder that is also progressive, similar to AD, and mainly affects the motor system, though non-motor symptoms are also prevalent
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Es besteht die Tendenz zu einer funktionellen Regulationsblockade auf hherem Niveau
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Without water present, the degradation pathways that destroy peptides in solution, hydrolysis, deamidation, oxidation, are dramatically slowed
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