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Reduced concentration of glutathione secondary to oxidative stress has also been described in bronchoalveolar lavage fluid (BAL) obtained from children with cystic fibrosis, with those experiencing an infective exacerbation having a further decreased concentration 37
pubmed.ncbi.nlm.nih.gov/16352683 Raun K, et al
[ 12 , 16 ] Researchers hypothesize that this mechanism could contribute to some of the sleep-related effects reported in early studies
564 Likewise, primary astrocytes prepared from ALS post-mortem samples induced necroptosis of neurones in co-culture, 565 and transplantation of diseased astrocytes into the spinal cord triggered motor deficits and promoted motor neurones degeneration
Following translocation of newly formed Nrf2 to the nucleus, KEAP1 mRNA levels, total Keap1 protein concentrations and Keap1 concentrations in the autophagosome increase
