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Mice were treated subcutaneously at the indicated doses with 5 l per g body weight of either Vehicle, Lani (CAS: 927961-18-0, MedChemExpress), semaglutide, GLP-1Lani, GLP-1Tesa, GLP-1GIP, GLP-1GIPTesa, GLP-1GIPLani, or co-administration of either GLP-1GIP plus Lani or GLP-1Lani plus acyl-GIP (Extended Data Fig
The chamber of Vitrobot was set to 100% humidity at 4 C
My PCP is overly cautious
Fiber also triggers GLP-1 by slowing gastric emptying since it digests slower
Then we computed using our model whether the functional hepatocytes ever declined below 30% in which case we predict death rather than recovery
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