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Non-alcoholic steatohepatitis or NASH is defined as macrovesicular steatosis with inflammatory changes and cellular injury with hepatocellular ballooning, with or without fibrosis
This was the most distinctive safety finding from TRIUMPH-4
With caution, the drug is prescribed to children and adolescents, pregnant and lactating women, as well as the elderly
For Wegovy, take the missed dose as soon as possible if it's at least 48 hours before your next scheduled dose
Secondary carnitine depletion due to increased formation and urinary excretion of glutarylcarnitine is suggested to play an important role in the neuropathogenesis of GCDH deficiency, inducing excitotoxic neuronal damage and mitochondrial dysfunction [83]
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