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According to the latest EASL Clinical Practice Guidelines, non-invasive scores, serum markers, liver stiffness and imaging methods should be used for ruling out rather than diagnosing advanced fibrosis in low-prevalence populations and should be preferentially employed in patients at risk of advanced liver fibrosis (63)

Chemical Peels Peels are useful for surface-level brightening, though they may require multiple sessions for more profound pigmentation

"Influence of must composition on phenolic oxidation kinetics"

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Comprehensive monitoring should include assessment of therapeutic response and screening for potential adverse effects, particularly signs of malignancy given the angiogenic effects