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Among the genes downregulated by more than 1.4-fold, a significant enrichment of functional pathways related to caveola, cytoskeleton organization, blood vessel and coagulation, as well as chromosomal proteins was observed

174 StokerM.GherardiE.PerrymanM.GrayJ

Briefly, in neoadjuvant settings, preoperative EsCu@NPs reduce tumor burden, decrease minimal residual disease, curb postsurgical recurrence and spontaneous lung metastasis, translating into prolonged survival

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The CAT gene encodes catalase, a crucial scavenger of hydrogen peroxide in human erythrocytes, which is dependent on the availability of PPP-derived NADPH (58)