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The experimental setup involved exposure of dermal fibroblasts to various combinations of GHK-Cu and HA, measuring the synthesis of collagen types I, IV, and VII

For the shoulder, where multiple structures may be involved in a single injury pattern, this enhanced sensitivity helps coordinate healing across different tissue types

Novo Nordisk filed an NDA for the CagriSema combination in December 2025, with an FDA decision anticipated in late 2026