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10.1016/j.cell.2006.05.047 74 HabanjarO.Diab-AssafM.Caldefie-ChezetF.DelortL

Ongoing phase 3 trials are studying the medication for: Type 2 diabetes Weight management Osteoarthritis Non-alcoholic fatty liver disease (NAFLD) Obstructive sleep apnea in obese and overweight adults

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Suanzaoren decoction improves depressive-like behaviors by regulating the microbiota-gut-brain axis via inhibiting TLR4/NFB/NLRP3 inflammation signal pathway

Dillman et al, 2013), and thus, there might be an ongoing requirement for KAT6A for brain function, which might also benefit from treatment increasing histone acetylation levels