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This modification renders the peptide resistant to enzymatic degradation, significantly extending its half-life and potency in vivo compared to standard L-peptides

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62 Immunotherapy resistance Although immune checkpoint blockade (ICB) therapies (e.g., anti-PD-1/PD-L1, anti-CTLA-4 antibodies) have revolutionized cancer treatment, both primary and acquired resistance remain major challenges (Fig

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Thng hiu: DHC - Nht Bn u im: - Hm lng va phi (500mcg/vin), khng qu cao nn ph hp vi nhiu i tng