When someone arrives with a significant deficiency, their stores are low, their red blood cells may be enlarged (macrocytosis), and, in longstanding cases, nerve function can be affected
Always talk to a healthcare provider about your specific situation
Factors like low stomach acid or certain health conditions can prevent your body from actually using the B12 you consume
Mechanistically, these changes appear to coincide with elevated NAD+ and activation of metabolic gene programs consistent with increased energy expenditure
Patients with autoimmune diseases : Autoimmune disorders that attack the digestive system, such as pernicious anemia, can prevent the body from absorbing adequate B12 Incorporating B12 into Your Neuropathy Treatment Its important to consult your doctor before adding any supplements, including Vitamin B12, to your neuropathy treatment plan