4.6.2 Retinal disease Diabetic retinopathy (DR) is the most prevalent microvascular complication of diabetes and the leading cause of preventable blindness among working-age individuals (81)
Data suggest that activation of GIP-R decreases inflammation in adipose tissue and cytokines levels (such as IL-6) and promotes the rise of serum adiponectin levels, a cytokine with anti-inflammatory effects and beneficial effects on diabetic nephropathy, which can explain potential beneficial effects on kidneys (even if GIP-R are not present) (47)
Research-based options include supporting vitamin B6 as P5P, GABA-producing probiotics, magnesium, taurine, glycine, and L-theanine, plus herbs such as passionflower, kava, lemon balm, bacopa, and magnolia bark
Responding to Browns report on the NOPs experiments with Androgel (which contains testosterone), Parker notes that: It will be interesting to determine the minimal amount of topical male hormone required to create a positive test, and asks whether there were other topical hormones that would create more dramatic results. To be clear: this is the CEO of the worlds largest athletic shoe and apparel company, not some skulking henchman
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