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Gastrointestinal adverse events, predominantly mild-to-moderate in severity, were more frequently reported with semaglutide compared to placebo (82.2% versus 53.9%)

GLP-1 medications improve insulin sensitivity in liver cells, reduce oxidative stress, and activate cellular cleaning processes like macroautophagy that help remove excess fat 19

Any of these scenarios diminishes the compound's efficacy

If you experience urinary incontinence while taking Ozempic, it is essential to consult your healthcare provider for personalized management strategies, which may include pelvic floor exercises and additional treatments

However, that figure is likely overestimated as some of these drugs will face generic or biosimilar competition