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Clinical Rationale for GLP-1RAs in T2DM It is well recognised that T2DM is a complex and multifactorial disorder attributable to the eight underlying pathophysiological defects labelled the ominous octet [7]
Europe GLP-1 Receptor Agonists Obesity Drugs Market Insight The Europe GLP-1 receptor agonists obesity drugs market is projected to grow at a substantial CAGR during the forecast period, fueled by the rising incidence of obesity, expanding reimbursement frameworks, and broader acceptance of pharmacological weight management
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These potential cardioprotective effects may be related to the favourable actions of metformin on lipid metabolism, vascular smooth muscle, hypercoagulation, platelet hyperactivity, cardiomyocyte intracellular calcium handling and endothelial function [24]
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