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Parkinsons disease is a well-known neurodegenerative problem after AD that is produced by dopaminergic alteration along with the production of -synuclein in the substantia nigra pars (SNpc)

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The rationale is borrowed from other compounds where tissue saturation and receptor dynamics justify phased dosing

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To view a copy of this licence, visit About this article Cite this article Karagiannis, T., Malandris, K., Avgerinos, I