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Affected hepatocytes are markedly enlarged
Results vary depending on individual factors such as starting weight, metabolism, adherence to the plan, and treatment choices
Some newer agents act not only on the GLP-1 receptor but also on additional targets, such as the glucose-dependent insulinotropic polypeptide (GIP) receptor
The consequent depletion of glutathione [3] impedes the efficient quenching of free radicals, leading to redox imbalance and oxidative stress [4]
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![Structures of (a) GLP-1, (b) GIP and (c) tirzepatide [19, 88, 90]](https://www.researchgate.net/publication/370926483/figure/fig4/AS:11431281185432337@1693619320519/Structures-of-a-GLP-1-b-GIP-and-c-tirzepatide-19-88-90-Amino-acids-are.png)
