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However, for a disease where current treatments remain unable to fully prevent progression or restore function, the peptide research pipeline offers genuine reasons for cautious optimism

Efficacy of antidepressants and psychological therapies in irritable bowel syndrome: systematic review and meta-analysis

The answer lies in the difference between central and peripheral effects

These effects are mediated through binding of calcitonin to a specific receptor (the calcitonin receptor or CTR) on the osteoclast (20), a specialized cell that resorbs bone, causing it to retract and cease bone resorption (21)

Its not speculation