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Hydroxocobalamin is a natural form of Vitamin B-12 that can be administered via injection to improve energy levels, aid in red blood cell development and help maintain a healthy central nervous system

Phase 2 clinical trial data published in the New England Journal of Medicine (Jastreboff et al., 2023) demonstrated mean body weight reductions of up to approximately 24% over 48 weeks in adults with obesity a notable finding, though long-term durability data and head-to-head comparisons with other treatments are not yet available

Clinically, B12 shots have long been used to treat cyanide poisoning

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Patients with early hereditary optic nerve atrophy, cyanocobalmin hypersensitivity, and those who are pregnant