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If you spot fragments, draw the solution through a 0.22 micron syringe filter before each injection, or discard the vial and reconstitute a fresh one
For a 5 mg vial, add 2.5 mL bacteriostatic water to create a 2 mg per mL concentration
Filler injections are often placed deeper, but most filler products come with lidocaine numbing mixed into their formulation, which causes numbs the area as its being treated
van Vollenhoven R (2019) Treat-to-target in rheumatoid arthritisAre we there yet
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