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Loss or mutation of p53 disrupts these pathways, promoting cellular immortalisation, checkpoint defects, and genomic instability, which allows replication of damaged DNA and contributes to tumourigenesis (35, 36)
**Who should consider it:** First-time GLP-1 users, patients who value an extensive safety track record, those with cardiovascular concerns, and anyone seeking the most affordable compounded option
Allow the vial to sit in the refrigerator for 30 to 60 minutes before adding water
Consistency and pairing with DHT blockers improves outcomes
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