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Total excision including up to 1 cm free margin is recommended without adjuvant chemotherapy or radiotherapy by most authors to achieve a cure [2]
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5xFAD : five familial APP + PS1 mutations, amyloid aggregates from 2 months, memory deficits from 4-6 months
Despite these promising findings, current evidence remains largely preclinical
CYP1A homologues also metabolize AFB 1 to produce the detoxified metabolite AFM 1 , whereas CYP3A enzymes - P450 III AY and in the fetal liver P450 III A6 , produce another detoxified metabolite, aflatoxin Q 1 (AFQ 1 ), the major metabolite of AFB 1 (Figure 2)
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