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In reality, successful obesity management depends on understanding: A comprehensive evaluation helps determine whether advanced therapies are appropriate and which approach is most likely to deliver sustainable results

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While this has some inherent logic, it has not been fully explored whether it is valid to assume a linearity of the relationship between gene and serum UA in which genetic polymorphisms differentiating normal and high UA associated with, say, risk of gout are the same as those differentiating normal and low UA associated with risk of PD