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A pharmacokinetic study cited in the amlodipine FDA label found that diltiazem (a moderate CYP3A4 inhibitor) increased amlodipine systemic exposure by 50% [1]
1 2 Plant Physiol
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Dunn, T
This facilitates oxidative phosphorylation, ultimately promoting GLP-1 secretion in enteroendocrine cells, thereby delineating a key mechanism for LEOs antidiabetic efficacy
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