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Llamas Dios, J
NAD therapy may aid mood regulation by supporting the balance of serotonin and noradrenaline, while also promoting new cell growth in areas of the brain affected by depression
For example, compared to age-matched women, men have 36, 28 and 82% greater concentrations of carnosine in soleus, gastrocnemius and tibialis anterior muscles, respectively (Everaert et al
Pros: Well-tolerated Generic and inexpensive Safe cardiovascular profile Cons: Dose restrictions for heart patients (max 20mg if over 60 or with certain heart conditions) Can affect heart rhythm at high doses Sexual side effects Typical dose: 10-40mg daily (lower for elderly or cardiac patients) Fluoxetine (Prozac): The Long-Acting One This works well for depression but has less specific cardiovascular outcome data
In vitro studies further support its therapeutic potential, showing that IGF-1 modulates inflammatory responses, stimulates tenocyte proliferation and migration, and enhances collagen synthesis (Gulotta and Rodeo, 2009
