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More studies are needed to explore this mechanism further, not least given the advent of medications targeting antioxidant systems which may be an important future therapeutic option in patients with MDD (Simon et al
TNF-, belonging to the Fas family, exhibits a robust interaction with the Fas ligand and triggers caspases, initiating programmed cell death (Bye et al., 2007)
In the usual course of things, a promising drug candidate would be ushered into human trials
10.1093/toxsci/57.1.177 91 SalducciM
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