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The biological activity of GIP in adipocytes has been investigated for some time, and although there is a need for better understanding, GIP is implicated in adipocyte carbohydrate and lipid metabolism through regulation of glucose uptake [30], lipolysis [31], and lipoprotein lipase (LPL) activity [32]
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When combined with lifestyle changes, lorcaserin was found to be effective in promoting significant weight loss and improving the maintenance of that weight loss compared to the placebo
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