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The reduction in glomerular filtrate Ca 2+ concentration and the increased reabsorption of Ca 2+ effects of the thiazides allows them to be used in the treatment of hypocalcemia and in the prevention of calcium oxalate stones associated with Dent disease
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The peptide also modulates MMP activity and expression, creating a balanced proteolytic environment that allows removal of damaged, fragmented collagen while protecting newly synthesized fibers
Wei, Microchimica Acta 186, (2019)
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