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ICH Q2(R2) Validation of analytical procedures Scientific guideline. EMA
It highlights DSIPs ability to block stress signals, enhance delta-wave sleep, and balance circadian rhythms
However, intravenous administration of synthetic DSIP in 6 middle-aged human chronic insomniacs with disturbed sleep brought very good results, as longer sleep, higher quality with fewer interruptions and slightly more REM sleep
Expert Opinion on Biological Therapy 12(1):37-51
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