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The exact mechanism is not fully understood, but semaglutide is thought to reduce appetite and increase feelings of fullness, leading to reduced calorie intake and weight loss
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Santos P, Herrmann AP, Benvenutti R, Noetzold G, Giongo F, Gama CS, et al
Notably, the authors suggested that semaglutide may reduce de novo collagen synthesis without causing degradation of pre-existing collagen fibers [29], implying that semaglutide may not improve existing fibrosis, but it may prevent the initiation and progression of fibrosis, which, however, needs other more focused studies to be definitively demonstrated
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