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The second mechanism by which glutathione causes lightening of skin is inhibition of transfer of tyrosinase to premelanosomes for melanin synthesis.[] The third mechanism of tyrosinase inhibition is through its antioxidant effect as it scavenges the free radicals generated in the epidermis following UV light irradiation
A diet with a lack of essential nutrients reduces glutathione synthesis
Besides antimicrobial peptides, synthetic amphiphilic polymer constituents can also be designed to disrupt bacterial membranes, leading to the efflux of intracellular substances and thus affecting the bacterias ability to survive [79]
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