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TGF- signaling is a key driver of this metabolic shift, upregulating enzymes such as PHGDH, PSAT1, PSPH, and SHMT1/2 that are essential for serineglycine biosynthesis and collagen production [17, 18]

In conclusion, the combination of HBV infection and alcohol use significantly worsens liver disease and increases cancer risk

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This process involved metabolic dysfunction that results in increased production of cytosolic and lipid ROS, independently of mitochondria

Low B12 levels are common, especially in people with restrictive diets, certain medical conditions, or high stress levels